Mass Spectroscopy History (brief)
MALDI-TOF MS is a very good, fast
and accurate technique at indicating a species of microbiological specimens. MALDI is also a very good process at creating gas
phase ions of proteins and peptides which can be identified in a mass spectrometer.
Mass spectrometry is a type of
scientific testing technique conducted in a laboratory. It is commonly used in
detecting bacterial isolates where it can use proteins biomarkers to find
differences at a species level. MALDI was founded in 1985 by Hillenkamp and
Karas in which they had found Alanine which is a type of a amino acid is easily
ionised if it was mixed with other types of amino acids such as Tryptophan
where it had absorbed the laser energy and had helped ionise the non absorbing
Alanine.
**REMEMBER TO STAY POSITIVE LIKE A PROTON!!**
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